Bioavailability of a dexlansoprazole delayed-release orally disintegrating tablet: effects of food and mode of administration
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منابع مشابه
Bioavailability of a dexlansoprazole delayed-release orally disintegrating tablet: effects of food and mode of administration
BACKGROUND Dexlansoprazole is a proton pump inhibitor (PPI) approved for use in dual delayed-release capsule and orally disintegrating tablet (ODT) formulations. AIM To assess effects of food, water, and route of administration on the bioavailability of dexlansoprazole 30-mg ODT. METHODS Two separate open-label, phase 1, single-dose crossover studies were conducted in healthy adults. In stu...
متن کاملFormulation and taste masking of Ranitidine orally disintegrating tablet
Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...
متن کاملFormulation and taste masking of Ranitidine orally disintegrating tablet
Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...
متن کاملPREVACID (lansoprazole) Delayed-Release Capsules PREVACID SoluTab (lansoprazole) Delayed-Release Orally Disintegrating Tablets For oral administration
-----------------------------DRUG INTERACTIONS-------------------------- • Atazanavir: Do not co-administer with atazanavir. (7.1) • Drugs with pH-Dependent Absorption: May interfere with the absorption of drugs where gastric pH is important for bioavailability. (7.1) • Warfarin: Concomitant warfarin use may require monitoring for increases in INR and prothrombin time. (7.2) • Tacrolimus: Conc...
متن کاملPharmacokinetics and pharmacodynamics of an orally disintegrating tablet formulation of dexlansoprazole
BACKGROUND The pharmacokinetics and pharmacodynamics of a novel orally disintegrating tablet (ODT) formulation of delayed-release dexlansoprazole 30 mg was evaluated versus the dexlansoprazole 30 mg capsule in this phase I, open-label, multiple-dose, randomized, two-period crossover study. METHODS Healthy adults received daily doses of 30 mg dexlansoprazole ODT or 30 mg dexlansoprazole delaye...
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ژورنال
عنوان ژورنال: Clinical and Experimental Gastroenterology
سال: 2017
ISSN: 1178-7023
DOI: 10.2147/ceg.s121129